Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery

NACompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

January 31, 2003

Primary Completion Date

March 31, 2005

Study Completion Date

March 31, 2009

Conditions
Schistosomiasis MansoniPortal HypertensionUpper Gastrointestinal Bleeding
Interventions
PROCEDURE

Endoscopic treatment

The presence of gastroesophageal varices was confirmed by fiberoptic esophagogastroduodenoscopy (EGD). In view of the experience of our service and local circumstances at the time of the study, the endoscopic treatment of choice was sclerotherapy, performed with a Teflon-sheathed metal needle. The sclerosing agent was 2.5% monoethanolamine oleate. Esophageal varices visible on EGD in the pre- and post-treatment period were classified as small, medium or large on the basis of criteria proposed by Paquet. All complications attributable to sclerotherapy were recorded.

PROCEDURE

Total EGDS+ endoscopy

Esophagogastric devascularization with splenectomy followed by endoscopic sclerotherapy of esophageal varices 2 months postoperatively.

Trial Locations (1)

57000000

Universidade Federal de Alagoas, Maceió

All Listed Sponsors
lead

Universidade Estadual de Ciências da Saúde de Alagoas

OTHER

NCT01931826 - Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery | Biotech Hunter | Biotech Hunter