Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy

PHASE4CompletedINTERVENTIONAL
Enrollment

254

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

December 31, 2018

Study Completion Date

December 31, 2018

Conditions
Chronic Hepatitis B
Interventions
DRUG

peg-interferon alpha 2b, 1.5mcg/kg s/c given weekly

DRUG

Nucleos(t)ide analogue therapy

Trial Locations (4)

Unknown

Changi General Hospital, Singapore

National University Hospital, Singapore

Singapore General Hospital, Singapore

Tan Tock Seng Hospital, Singapore

All Listed Sponsors
collaborator

Tan Tock Seng Hospital

OTHER

collaborator

Singapore Clinical Research Institute

OTHER

collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Singapore General Hospital

OTHER

collaborator

Changi General Hospital

OTHER

lead

Seng Gee Lim

OTHER

NCT01928511 - Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy | Biotech Hunter | Biotech Hunter