Study of the Effects of Negative Emotions on Endothelial Function

NACompletedINTERVENTIONAL
Enrollment

280

Participants

Timeline

Start Date

September 1, 2013

Primary Completion Date

November 1, 2020

Study Completion Date

November 1, 2020

Conditions
EmotionsEndothelial Dysfunction
Interventions
OTHER

Anger Induction

The participant is asked to recall an incident in the recent past during which they became moderately to extremely angry, or is asked to read statements out loud evoking moderate to extreme feelings of anger. The participant is asked to take a few moments to bring the details of the incident to mind and, when ready, to describe the incident in great detail to the experimenter. Participants are asked to describe key elements, such as any dialogue that transpired during the incident, along with other details of the incident, particularly regarding the feelings of that particular emotion experienced at the time. In so doing, the experimenter works to re-elicit the emotions that accompanied the original incident. The duration of the negative emotion induction task is 8 minutes.

OTHER

Depressed Mood Induction

The participant will be asked to undergo a validated depression/sadness induction task.

OTHER

Anxiety Induction

The participant will be asked to undergo a validated anxiety induction task.

OTHER

Neutral emotion task

This is a neutral control task that each of the negation emotion induction tasks will be compared to.

Trial Locations (1)

10032

Columbia University Medical Center, New York

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Columbia University

OTHER

NCT01909895 - Study of the Effects of Negative Emotions on Endothelial Function | Biotech Hunter | Biotech Hunter