Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib

PHASE3CompletedINTERVENTIONAL
Enrollment

707

Participants

Timeline

Start Date

September 26, 2013

Primary Completion Date

October 16, 2017

Study Completion Date

January 12, 2021

Conditions
Hepatocellular Carcinoma
Interventions
DRUG

Cabozantinib tablets

DRUG

Placebo tablets

Trial Locations (104)

7

Dublin

100

Taipei

128

Rome

168

Rome

736

Liuying Township

1003

Auckland

2010

Darlinghurst

2050

Camperdown

2139

Concord

2145

Westmead

2217

Kogarah

2650

Edegem

3050

Melbourne

3293

Elche

4000

Liège

5037

Kurralta Park

6000

Perth

6202

Nice

7100

La Louvière

9000

Ghent

10032

New York

10065

New York

10595

Valhalla

13353

Berlin

16132

Genoa

20089

Rozzano

20122

Milan

22030

Edirne

25000

Besançon

27100

Gaziantep

28007

Madrid

28041

Madrid

28222

Majadahonda

28850

Torrejón de Ardoz

30318

Atlanta

32610

Gainesville

33075

Bordeaux

35128

Padua

39120

Magdeburg

40138

Bologna

40705

Taichung

47014

Meldola

47900

Rimini

48018

Faenza

50009

Zaragoza

55905

Rochester

59037

Lille

60590

Frankfurt am Main

60637

Chicago

63003

Clermont-Ferrand

63110

St Louis

64128

Kansas City

69317

Lyon

72076

Tübingen

73730

Esslingen am Neckar

75246

Dallas

78215

San Antonio

80054

Amiens

81675

München

89109

Las Vegas

90033

Los Angeles

90127

Palermo

92123

San Diego

92879

Corona

94010

Créteil

94115

San Francisco

96815

Honolulu

98104

Seattle

98109

Seattle

99208

Spokane

119074

Singapore

169610

Singapore

308433

Singapore

400015

Cluj-Napoca

500019

Brasov

01805

Burlington

07018

East Orange

T2N 4N2

Calgary

M5G 2M9

Toronto

S7N 4H4

Saskatoon

Unknown

Freiburg im Breisgau

Hong Kong

6229 HX

Maastricht

1081 HV

Amsterdam

1105 AZ

Amsterdam

2333 ZA

Leiden

10-513

Olsztyn

41-400

Mysłowice

60-569

Poznan

410-769

Goyang

602-739

Busan

463-707

Seongnam

110-744

Seoul

120-752

Seoul

135-710

Seoul

136-705

Seoul

137-701

Seoul

138-736

Seoul

443-721

Suwon

CH63 4JY

Metropolitan Borough of Wirral

B15 2TH

Birmingham

NW3 2QG

London

SE5 9RS

London

M20 4BX

Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Exelixis

INDUSTRY