Ranitidin Versus Omeprazole in Patients Taking Clopidogrel

PHASE4CompletedINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

June 30, 2013

Study Completion Date

June 30, 2013

Conditions
Coronary Artery DiseaseDrug Interaction Potentiation
Interventions
DRUG

omeprazole

Influence of omeprazole on clopidogrel pharmacodynamics will be evaluated.

DRUG

Ranitidine

Influence of ranitidine on clopidogrel pharmacodynamics will be evaluated.

DRUG

Clopidogrel

Clopidogrel added to ASA therapy at the first medical visit, Open label 75 mg once a day will be given to all individuals as part of the protocol (since main outcome of interest is clopidogrel effect. Actual comparison arms are double blind ranitidine and omeprazole

All Listed Sponsors
collaborator

InCor Heart Institute

OTHER

lead

University of Sao Paulo General Hospital

OTHER

NCT01896557 - Ranitidin Versus Omeprazole in Patients Taking Clopidogrel | Biotech Hunter | Biotech Hunter