NCT01895244View on ClinicalTrials.gov

Autologous Stem Cell Transplantation for Progressive Systemic Sclerosis

PHASE2CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

September 30, 2012

Primary Completion Date

September 30, 2021

Study Completion Date

June 30, 2024

Conditions
SclerodermaCardiac InvolvementAutologous Stem Cell Transplantation
Interventions
DRUG

Autologous stemcell transplantation with CD (cluster of differentiation) 34 selected stem cells

If no active alveolitis: mobilisation with 2x1g Cyclophosphamide If active alveolitis: mobilisation with 2x1.5g Cyclophosphamid If cardiac manifestation: Conditioning with CYC 2 x 50mg + thiotepa 2x5mg + ATG If no cardiac manifestation: Conditioning with 4 x 50mg CYC + ATG

Trial Locations (1)

72076

University Hospital Tuebingen; Department of oncology, hematology, rheumatology, immunology and pulmology, Tübingen

All Listed Sponsors
lead

University Hospital Tuebingen

OTHER

NCT01895244 - Autologous Stem Cell Transplantation for Progressive Systemic Sclerosis | Biotech Hunter | Biotech Hunter