Study to Assess the Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours and Normal Liver Function or Mild or Moderate Liver Impairment

PHASE1CompletedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

March 13, 2014

Primary Completion Date

November 29, 2016

Study Completion Date

March 30, 2017

Conditions
Solid Tumours
Interventions
DRUG

Olaparib tablet dosing

Part A - single 300mg oral dose olaparib (administered as 2x150mg tablets) Part B - 300mg oral dose olaparib (administered as 2x150mg tablets) bd

Trial Locations (12)

21079

Research Site, Dijon

33075

Research Site, Bordeaux

33076

Research Site, Bordeaux

38043

Research Site, Grenoble

69373

Research Site, Lyon

75651

Research Site, Paris

656 53

Research Site, Brno

1066 CX

Research Site, Amsterdam

6202 AZ

Research Site, Maastricht

06591

Research Site, Seoul

Unknown

Research Site, London

SM2 5PT

Research Site, Sutton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY