NCT01891084View on ClinicalTrials.gov

The Benefit and Harm of Fever Suppression by Antipyretics in Influenza

PHASE4CompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

July 31, 2013

Primary Completion Date

December 31, 2018

Study Completion Date

December 31, 2018

Conditions
Influenza
Interventions
DRUG

Paracetamol

Paracetamol 1 tablet (500mg) four times daily. For a maximum period of 5 days if the patient is still having fever. When required, participants may take up to 2 tablets (1gm) in each dose.

DRUG

Placebo

(Identical-looking) Placebo 1 tablet four times daily. For a maximum period of 5 days if the patient is still having fever. When required, participants may take up to 2 tablets in each dose.

DRUG

Backup NSAID ibuprofen

Backup NSAID ibuprofen 200mg orally every 8 hourly will also be provided to all participants, which can be taken when necessary (PRN) if the participant finds the fever intolerable.

Trial Locations (1)

Unknown

University Health Service, The Hong Kong Polytechnic University, Hong Kong, Hksar

All Listed Sponsors
lead

The University of Hong Kong

OTHER

NCT01891084 - The Benefit and Harm of Fever Suppression by Antipyretics in Influenza | Biotech Hunter | Biotech Hunter