Study to Investigate if the Uptake of Ticagrelor Into the Body Differs Depending on Method of Administration.

PHASE1CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

July 31, 2013

Primary Completion Date

September 30, 2013

Study Completion Date

September 30, 2013

Conditions
Bioavailability Heathy Volunteers
Interventions
DRUG

Ticagrelor 90 mg whole tablet

Ticagrelor 90 mg whole tablet administered as a single oral dose

DRUG

Ticagrelor 90 mg tablet crushed

Ticagrelor 90 mg crushed and suspended in water

DRUG

Dispersed ticagrelor 90 mg tablet suspended in water - nasogastric tube

Dispersed 90 mg ticagrelor 90 mg tablet suspended in water and administered through a nasogastric tube into the stomach

Trial Locations (1)

Unknown

Research Site, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY