Efficacy and Safety of TV-1380 as Treatment for Facilitation of Abstinence in Cocaine-Dependent Subjects

PHASE2CompletedINTERVENTIONAL
Enrollment

208

Participants

Timeline

Start Date

June 30, 2013

Primary Completion Date

September 30, 2014

Study Completion Date

October 31, 2014

Conditions
Cocaine Addiction
Interventions
DRUG

TV-1380 150 mg

Subjects assigned to TV-1380 150 mg will be administered one intra-muscular (IM) injection once weekly over 12 weeks. The injection volume will be the same for all treatment groups. Therefore, to accommodate the volume required for the highest dosing group (3.0 mL), subjects in this group will receive 3.0 mL IM injection of TV-1380 150 mg (1.5 mL TV-1380 and 1.5 mL placebo/diluents).

DRUG

TV-1380 300 mg

Subjects assigned to TV-1380 300 mg will be administered one intra-muscular (IM) injection once weekly over 12 weeks. Subjects in this treatment group will receive 3.0 mL TV-1380.

DRUG

Placebo

Subjects assigned to placebo will be administered one intra-muscular (IM) injection once weekly over 12 weeks. Subjects in this treatment group will receive 3.0 mL placebo.

Trial Locations (19)

Unknown

Teva Investigational Site 10663, Los Angeles

Teva Investigational Site 10665, Oceanside

Teva Investigational Site 10659, San Francisco

Teva Investigational Site 10746, Torrance

Teva Investigational Site 10664, North Miami

Teva Investigational Site 10661, Boston

Teva Investigational Site 10668, New Bedford

Teva Investigational Site 10747, St Louis

Teva Investigational Site 10745, Las Vagas

Teva Investigational Site 10667, Marlton

Teva Investigational Site 10662, Columbus

Teva Investigational Site 10660, Pittsburgh

Teva Investigational Site 10658, Charleston

Teva Investigational Site 10666, Salt Lake City

Teva Investigational Site 31064, Alicante

Teva Investigational Site 31063, Barcelona

Teva Investigational Site 31065, Barcelona

Teva Investigational Site 31069, Barcelona

Teva Investigational Site 31068, Madrid

All Listed Sponsors
lead

Teva Branded Pharmaceutical Products R&D, Inc.

INDUSTRY

NCT01887366 - Efficacy and Safety of TV-1380 as Treatment for Facilitation of Abstinence in Cocaine-Dependent Subjects | Biotech Hunter | Biotech Hunter