312
Participants
Start Date
November 12, 2013
Primary Completion Date
June 30, 2019
Study Completion Date
June 30, 2019
Long-term mild hypothermia
Hypothermia will be induced within 6 hours of injury and maintained at 34-35℃ for 5 days.Then the patients will be passively rewarmed to a temperature of 36 to 37˚C at a rate no greater than 0.5˚C/4 hours.
Normothermia
Patients assigned to the normothermia group will be kept at 36-37℃.
Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai
First Affiliated Hospital of Zhejiang University
OTHER
West China Hospital
OTHER
Second Affiliated Hospital of Wenzhou Medical University
OTHER
The 101st Hospital of Chinese People's Liberation Army
OTHER
The 98 Hospital of People's Liberation Army
UNKNOWN
Shenzhen Second People's Hospital
OTHER
The 94 Hospital of People's Liberation Army
UNKNOWN
Nanfang Hospital, Southern Medical University
OTHER
The Affiliated Hospital of Medical College of Chinese People's Armed Police Forces
UNKNOWN
Xiangya Hospital of Central South University
OTHER
Taizhou First People's Hospital
OTHER
Tang-Du Hospital
OTHER
Qilu Hospital of Shandong University
OTHER
Chongqing Emergency Medical Center
OTHER
Xuzhou Central Hospital
OTHER
The Affiliated Hospital Of Southwest Medical University
OTHER
RenJi Hospital
OTHER