A Randomised Controlled Clinical Trial of Memory Specificity Training (MEST) for Depression

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

July 31, 2013

Primary Completion Date

August 31, 2016

Study Completion Date

October 31, 2016

Conditions
Major Depressive DisorderDepressive Symptoms
Interventions
BEHAVIORAL

Memory Specificity Training

This intervention is a manualised, structured treatment delivered over 5 x 60 minute sessions to groups of 5-8 individuals. This treatment involves repeated practice of retrieving specific autobiographical memories in response to positive, negative and neutral cue words. There is a single psychoeducation component in the first session about memory difficulties common in depression which provides the rationale for this treatment. The training is supplemented by weekly homework practice.

BEHAVIORAL

Education and Support

The education-and-support comparison condition is matched with the experimental arm for length and format (ie., 5 x 60 minute weekly sessions in groups of 5-8 individuals). Groups receive a single psychoeducation component where information about depression is provided. This is followed by non-directive support where participants are encouraged to raise different kinds of events that occur each week for discussion in the group. The sessions are supplemented by a homework diary where participants will be invited to note down an event that occurs each day, which may be positive, negative, or benign and non-emotional in nature. This material will provide the basis for discussion in the weekly group meetings.

Trial Locations (1)

2022

Aliza Werner-Seidler, Sydney

Sponsors
All Listed Sponsors
collaborator

KU Leuven

OTHER

lead

Medical Research Council

OTHER_GOV

NCT01882452 - A Randomised Controlled Clinical Trial of Memory Specificity Training (MEST) for Depression | Biotech Hunter | Biotech Hunter