Periodontal Treatment Response in Type II Diabetic Patients

CompletedOBSERVATIONAL
Enrollment

74

Participants

Timeline

Start Date

June 30, 2012

Primary Completion Date

December 31, 2015

Study Completion Date

December 31, 2015

Conditions
Type II DiabetesPeriodontal Disease
Interventions
DRUG

Triclosan containing toothpaste

Type II diabetic patients will be instructed to brush their teeth at the same time day and with the same frequency as usual for them using only the triclosan containing toothpaste provided to them. Additional tubes of triclosan containing toothpaste will be provided to the participants for the duration of the study as needed. Following their baseline appointment, patients will be asked to return at 6 weeks, 3, 6, 9 and 12 months for an oral exam and dental cleaning. Samples will be collected at baseline, 3, 6 and 12 months. Samples collected may include venous blood, gingival crevicular fluid, plaque and saliva. Female study participants may be asked to perform a pregnancy test.

DRUG

Non-triclosan containing toothpaste

Type II diabetic patients will be instructed to brush their teeth at the same time day and with the same frequency as usual for them using only the non-triclosan containing toothpaste (i.e. placebo) provided to them. Additional tubes of non-triclosan containing toothpaste will be provided to the participants for the duration of the study as needed. Following their baseline appointment, patients will be asked to return at 6 weeks, 3, 6, 9 and 12 months for an oral exam and dental cleaning. Samples will be collected at baseline, 3, 6 and 12 months. Samples collected may include venous blood, gingival crevicular fluid, plaque and saliva. Female study participants may be asked to perform a pregnancy test.

Trial Locations (1)

32610

University of Florida, Gainesville

All Listed Sponsors
collaborator

Colgate Palmolive

INDUSTRY

lead

University of Florida

OTHER

NCT01881074 - Periodontal Treatment Response in Type II Diabetic Patients | Biotech Hunter | Biotech Hunter