Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

August 31, 2013

Primary Completion Date

July 31, 2018

Study Completion Date

July 31, 2018

Conditions
Colorectal CancerHead and Neck Cancer
Interventions
DRUG

Doxycycline

Doxycycline capsule, 100 mg, taken twice daily

DRUG

Hydrocortisone 1% cream

Applied to the face, hands, feet, neck, back, and chest each evening (Topical cream)

OTHER

Sunscreen

Applied to exposed skin areas at least 30 minutes before going outdoors each morning.

OTHER

Moisturizer

Applied to the face, hands, feet, neck, back, and chest each morning after sunscreen

DRUG

Clindamycin

Recommended for daily use if rash returns (Topical cream)

DRUG

Medrol-dose pack (Steroid)

Patients will receive a Medrol dose-pack while continuing the extensive treatment regimen.

Trial Locations (1)

40202

James Graham Brown Cancer Center, Louisville

All Listed Sponsors
collaborator

James Graham Brown Cancer Center

OTHER

lead

University of Louisville

OTHER

NCT01874860 - Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients | Biotech Hunter | Biotech Hunter