Bortezomib in Late Antibody-mediated Kidney Transplant Rejection

PHASE2CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

December 31, 2013

Primary Completion Date

February 28, 2015

Study Completion Date

February 28, 2017

Conditions
Late Rejection of Renal TransplantAntibody-mediated Rejection
Interventions
DRUG

Bortezomib

"Patients will receive two cycles of Bortezomib (Velcade®) at an interval of three months.~Each cycle will consist of intravenously administered (within 3-5 seconds) Bortezomib 1.3 mg/m2 twice weekly on days 1, 4, 8 and 11."

DRUG

Placebo

"Patients will receive two cycles of Placebo (NaCl solution) at an interval of three months.~Each cycle will consist of intravenously administered (within 3-5 seconds) Placebo twice weekly on days 1, 4, 8 and 11."

Trial Locations (1)

1090

Medical University of Vienna, Department of Nephrology and Dialysis, Vienna

All Listed Sponsors
collaborator

Medical University Innsbruck

OTHER

lead

Medical University of Vienna

OTHER

NCT01873157 - Bortezomib in Late Antibody-mediated Kidney Transplant Rejection | Biotech Hunter | Biotech Hunter