51
Participants
Start Date
August 31, 2013
Primary Completion Date
November 30, 2018
Study Completion Date
November 30, 2018
golimumab
golimumab 50mg subcutaneous injections (in combination with methotrexate), once a month, for a period of 22 weeks
methotrexate
Methotrexate will be started at a dosage of 15 mg/week orally and, if well tolerated, increased to 20mg/week at week 4 and 25mg/week at week 8 of the trial. If well tolerated, the maximum dose of 25 mg/week will be sustained until end of study (week 50). Folic acid 5 mg/week will be administered orally one day after the MTX intake.
Reade, Amsterdam
Academic Medical Center/University of Amsterdam, Amsterdam
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
OTHER