Clinical Trial of Efficacy and Safety of Subetta in the Combined Treatment of Patients With Type I Diabetes Mellitus

PHASE4CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

May 7, 2013

Primary Completion Date

July 31, 2016

Study Completion Date

July 10, 2016

Conditions
Type I Diabetes Mellitus
Interventions
DRUG

Subetta

"Each Subetta tablet contains a mixture of affinity purified polyclonal antibodies to β-subunit of the rINS (6 mg) and antibodies to eNOS (6 mg) in released-active form produced by the patented technology in accordance with the applicable European Pharmacopeia requirements.~Standard therapy of type I diabetes mellitus + Subetta (1 tablet 4 times a day) for 36 weeks.~Subetta: oral administration, per 1 intake - 1 tablet (keep in the mouth until complete dissolution, not at mealtime)."

DRUG

Placebo

"Placebo (identical to Subetta in shape and taste tablet containing exсipients). Standard therapy of type I diabetes mellitus + Placebo (1 tablet 4 times a day) for 36 weeks.~Placebo: oral administration, per 1 intake - 1 tablet (keep in the mouth until complete dissolution, not at mealtime)."

Trial Locations (15)

111123

"State Healthcare Institution of Moscow Central research institute of gastroenterology of Department of health care of Moscow", Moscow

119991

"State Educational Institution of Higher Professional Education Moscow State Medical Academy named after I.M. Sechenov", Moscow

129128

"Nonstate Health Care Institution Central Clinical Hospital №2 named after N.A. Semashko of Public Limited Company Russian Railways", Moscow

141400

"Municipal budgetary authority Khimki Central Clinical Hospital", Moscow Region

150062

"State Budgetary Health Care Institution of Yaroslavl Region Regional Сlinical Hospital", Yaroslavl

190013

"Private company Polyclinic Complex", Saint Petersburg

191482

"St. Petersburg State Budgetary Health Care Institution City Polyclinic №6", Saint Petersburg

195257

"St. Petersburg State Budgetary Health Care Institution Saint Venerable Martyr Elizaveta Municipal Hospital", Saint Petersburg

197022

"State Budgetary Educational Institution of High Professional Training St. Petersburg State Medical University named after academician I.P. Pavlov of Ministry of Health of Russian Federation, Therapy Faculty Board", Saint Petersburg

197183

"St. Petersburg Sate Budgetary Institution Consultative-Diagnostic Polyclinic №1 of Coastal Area", Saint Petersburg

344022

"State Budgetary Educational Institution of High Professional Training Rostov State Medical University of Ministry of Health of Russian Federation, Department of Endocrinology", Rostov-on-Don

394018

"Independent Health Care Institution of Voronezh Region Voronezh Regional Clinical Consultative-Diagnostic Center", Voronezh

443067

"Co.Ltd Diabet Center", Samara

603011

"The State Budgetary Institution of Health Care of the Nizhny Novgorod Region City clinical hospital No. 10 ", Nizhny Novgorod

603126

"Nizhny Novgorod regional State Budgetary Health Institution Nizhny Novgorod regional Clinical Hospital named after N.A. Semashko ", Nizhny Novgorod

Sponsors
All Listed Sponsors
lead

Materia Medica Holding

INDUSTRY

NCT01868594 - Clinical Trial of Efficacy and Safety of Subetta in the Combined Treatment of Patients With Type I Diabetes Mellitus | Biotech Hunter | Biotech Hunter