Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)

PHASE3CompletedINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

April 18, 2013

Primary Completion Date

May 9, 2021

Study Completion Date

January 17, 2025

Conditions
Opsoclonus Myoclonus SyndromeNeuroblastoma
Interventions
DRUG

Dexamethasone acetate

"First step:~immunosuppressive treatment with dexamethasone"

DRUG

dexamethasone and cyclophosphamide

second step (in case of insufficient response): immunosuppressive treatment with dexamethasone and cyclophosphamide

DRUG

dexamethasone and rituximab

third step (in case of insufficient response): immunosuppressive treatment with dexamethasone and rituximab

Trial Locations (36)

1090

St. Anna Kinderkrebsforschung e.V. CHILDREN'S CANCER RESEARCH INSTITUTE, Vienna

8032

Kinderspital Zurich, Zurich

13385

Hopita D'Enfants de La Timone, Marseille

14033

CHU CAEN, Caen

16148

G. Gaslini Institut, Genova

21079

Chu Dijon, Dijon

22185

University Hospital Lund, Lund

25030

Hopital Jean Minjoz, Besançon

30120

The Fundación para la Formación e Investigación Sanitarias de la Región de Murcia, El Palmar

31059

Chu Toulouse Hopital Des Enfants, Toulouse

33076

Chr Pellegrin, Bordeaux

34295

Hopital Arnaud de Villeneuve, Montpellier

35056

Chu Hopital Sud, Rennes

37044

Chu Tours Hopital Clocheville, Tours

38045

Chu de Grenoble, Grenoble

42055

Chu Saint Etienne, Saint-Etienne

44093

Chr de Nantes, Nantes

49933

Chu Angers, Angers

51092

Chu de Reims, Reims

54500

Hopital Nancy Brabois, Vandœuvre-lès-Nancy

59020

Centre Oscar Lambret, Lille

63003

Chu D'Estaing, Clermont-Ferrand

67098

CHU DE STRASBOURG HOPITAL Hautepierre, Strasbourg

69373

Centre Leon Berard, Lyon

75005

Institut Curie, Paris

75571

Ch Trousseau, Paris

76031

Chu de Rouen, Rouen

80054

Chu Amiens, Amiens

86021

Chu de Poitiers, Poitiers

87042

Chu de Limoges, Limoges

94275

Chu de Bicetre, Le Kremlin-Bicêtre

94805

Institut de Cancerologie Gustave Roussy, Villejuif

97400

CHU LA REUNION Site Félix Guyon, Saint-Denis

06202

Chu de Nice Archet 2, Nice

CH 3010

Universitätskinderklinik, Bern

0X3 9DU

John Radcliffe Hospital, Oxford

All Listed Sponsors
lead

Institut Curie

OTHER

NCT01868269 - Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg) | Biotech Hunter | Biotech Hunter