A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma

PHASE3CompletedINTERVENTIONAL
Enrollment

658

Participants

Timeline

Start Date

June 30, 2013

Primary Completion Date

May 22, 2015

Study Completion Date

January 15, 2021

Conditions
Renal Cell Carcinoma
Interventions
DRUG

Cabozantinib tablets

DRUG

Everolimus (Afinitor) tablets

Trial Locations (205)

7

Dublin

24

Dublin

290

Helsinki

1000

Brussels

1090

Vienna

1100

Vienna

1122

Budapest

2010

Darlinghurst

2020

Antwerp

2031

Randwick

2076

Wahroonga

2139

Concord

2145

Westmead

2217

Kogarah

2820

Bonheiden

2930

Brasschaat

3000

Leuven

3128

Box Hill

3165

Bentleight East

3690

Wodonga

4000

Liège

4010

Linz

4064

Milton

4102

Wooloongabba

5000

Adelaide

5004

Szolnok

6500

Ankara

7000

Hobart

8800

Roeselare

10065

New York

12200

Berlin

12206

Albany

13273

Marseille

14076

Caen

15232

Pittsburgh

15706

Santiago de Compostela

16132

Genoa

19111

Philadelphia

20007

Washington D.C.

20246

Hamburg

21201

Baltimore

21287

Baltimore

22710

Durham

25030

Besançon

27100

Gaziantep

28034

Madrid

28041

Madrid

28050

Seville

28922

Madrid

29425

Charleston

30605

Hanover

31008

Pamplona

31052

Toulouse

33006

Oviedo

33075

Bordeaux

33136

Miami

33176

Miami

33332

Gütersloh

33486

Boca Raton

33612

Tampa

34365

Istanbul

35042

Rennes

35100

Izmir

37203

Nashville

37232

Nashville

37920

Knoxville

38120

Memphis

41124

Modena

43210

Columbus

44106

Cleveland

44195

Cleveland

44805

Nantes

45122

Essen

46010

Valencia

47014

Meldola

48100

Ravenna

48109

Ann Arbor

48201

Detroit

48202

Detroit

52074

Aachen

52100

Arezzo

52242

Iowa City

55131

Mainz

55905

Rochester

60590

Frankfurt am Main

60611

Chicago

60612

Chicago

60637

Chicago

63110

St Louis

66205

Westwood

69120

Heidelberg

70124

Bari

72000

Le Mans

72076

Tübingen

75246

Dallas

75908

Paris

76022

Bedford

76104

Fort Worth

77024

Houston

77030

Houston

78229

San Antonio

78731

Austin

79106

Freiburg im Breisgau

80045

Aurora

80218

Denver

81377

Munich

81675

München

84112

Salt Lake City

85234

Gilbert

85259

Scottsdale

85724

Tucson

89075

Ulm

89148

Las Vegas

90048

Los Angeles

90095

Los Angeles

91010

Duarte

91054

Erlangen

92093

La Jolla

94589

Vallejo

94805

Villejuif

96008

Lyon

97213

Portland

97239

Portland

98109

Seattle

98684

Vancouver

98902

Yakima

99089

Erfurt

Jena

99503

Anchorage

115478

Moscow

150040

Yaroslavl

196247

Saint Petersburg

644013

Omsk

Unknown

Birmingham

Port Macquarie

Santiago

Seoul

Stockholm

Umeå

Taichung

Taipei

London

Glasgow

06520

New Haven

Orlando

02215

Boston

B1900BAJ

La Plata

B7600LTO

Mar del Plata

T2N 4N2

Calgary

T6G 1Z2

Edmonton

V5Z 4E6

Vancouver

R3A 1R9

Winnepeg

B3H 1V7

Halifax

L8V 5C2

Hamilton

K7L 5P9

Kingston

N6A 4L6

London

L1G 2B9

Oshawa

K1H 8L6

Ottawa

M4N 3M5

Toronto

M5G 2N2

Toronto

H2L 4M1

Montreal

S7N 4H4

Saskatoon

775 20

Olomouc

656 91

Brno

128 08

Prague

DK-2730

Herlev

DK-8000

Aarhus

DK-5000

Odense

FI-20520

Turku

01307

Dresden

00128

Rome

00152

Rome

Lombardia

Cremona

05100

Terni

6229 HX

Maastricht

1066 CX

Amsterdam

2333 ZA

Leiden

3045 PM

Rotterdam

60-569

Poznan

15-027

Bialystok

80-210

Gdansk

04-909

Warsaw

1500-650

Lisbon

1649-035

Lisbon

200-072

Porto

08001

Prešov

01207

Žilina

110-744

Seoul

120-752

Seoul

08003

Badalona

08025

Barcelona

08907

L'Hospitalet de Llobregat

08035

Barcelona

Málaga

Málaga

SE-22185

Lund

B15 2TH

Birmingham

DE22 3NE

Derby

GU2 7XX

Guildford

EC1A 7BE

London

SE1 9ER

London

M20 4BX

Manchester

CH63 4JY

Metropolitan Borough of Wirral

HA6 2RN

Northwood

AB25 2ZN

Aberdeen

EH4 2XU

Edinburgh

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Exelixis

INDUSTRY

NCT01865747 - A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma | Biotech Hunter | Biotech Hunter