NCT01865357View on ClinicalTrials.gov

Prospective Longitudinal 1-year Study of the Correlation Between Cognitive Functioning in Patients With Clinically Isolated Syndrome Suggestive of Multiple Sclerosis and Disconnection in the Brain Assessed by MRI

NACompletedINTERVENTIONAL
Enrollment

117

Participants

Timeline

Start Date

August 24, 2012

Primary Completion Date

December 1, 2016

Study Completion Date

December 1, 2016

Conditions
Clinically Isolated Demyelinating SyndromesMultiple SclerosisCognitive DeficienciesBrain MRI
Interventions
OTHER

Brain MRI - Clinical and cognitive evaluation

"* Clinical evaluation (EDSS, MSFC)~* Cognitive evaluation with tests of information processing speed, attention, working memory, episodic memory and executive functions, assessment of confounding factors (depression (BDI) and anxiety (HAD), mood (EHD), fatigue (M-FIS) and assessment of quality of life (SEP-59)~* Brain MRI (3 Tesla): FLAIR, 3D MPRAGE T1 and DTI"

OTHER

Eye movement

Assessment of eye Movements (EyeBrain software) for only the group of 15 healthy subjects at baseline and at 12 months

Trial Locations (1)

33000

CHU de Bordeaux, Bordeaux

All Listed Sponsors
collaborator

TEVA laboratories

UNKNOWN

lead

University Hospital, Bordeaux

OTHER

NCT01865357 - Prospective Longitudinal 1-year Study of the Correlation Between Cognitive Functioning in Patients With Clinically Isolated Syndrome Suggestive of Multiple Sclerosis and Disconnection in the Brain Assessed by MRI | Biotech Hunter | Biotech Hunter