Investigation Into the Role of GTN & RIPC in Cardiac Surgery

PHASE3CompletedINTERVENTIONAL
Enrollment

192

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

October 31, 2018

Study Completion Date

February 28, 2019

Conditions
Myocardial Reperfusion Injury
Interventions
OTHER

Remote ischaemic preconditioning

3 cycles of 5 minutes to arm and legs

DRUG

IV Normal saline

Normal saline IV started prior to knife to skin at a rate of 2-5 mls/h and stopped just after weaning off bypass.

DRUG

IV Glyceryl trinitrate 2-5ml/h

IV GTN given during surgery started prior to knife to skin and stopped after weaning off cardiopulmonary bypass.

Trial Locations (1)

NW1 2PG

The Heart Hospital, UCL Hospitals NHS Trust, London

All Listed Sponsors
collaborator

University College London Hospitals

OTHER

lead

University College, London

OTHER

NCT01864252 - Investigation Into the Role of GTN & RIPC in Cardiac Surgery | Biotech Hunter | Biotech Hunter