Phase 2 Trial of Pertuzumab and Trastuzumab With Weekly Paclitaxel and Chemotherapy for HER2 Positive Breast Cancer

First dose is 840mg, maintenance dose is 420mg. Pertuzumab will be administered once every 3 weeks for 24 weeks (8 doses total)

"For weeks 1-12, first dose is 4 mg/kg, maintenance dose is 2 mg/kg administered every week (12 doses total).~For weeks 13-24, dose is 6mg/kg administered every 3 weeks (4 doses total)."

Administered at 80mg/m2 every week from week 1 to 12 (12 doses total).

Administered at 500 mg/m2 for every 3 weeks during weeks 13-24 (4 doses total).

Administered at 75mg/m2 every 3 weeks during weeks 13-24 (4 doses total).

Administered at 500mg/m2 for every 3 weeks during weeks 13-24 (4 doses total).