103
Participants
Start Date
January 31, 2013
Primary Completion Date
April 30, 2014
Study Completion Date
November 30, 2014
PGD granules
The preparation of Peony-Glycyrrhiza Decoction (PGD) granules is in compliance with Pharmacopoeia of the People's Republic of China and Good Manufacturing Practice (GMP). Briefly, sliced, broiled Paeoniae Alba Radix and Glycyrrhizae Radix in a ratio of 1:1 in weight will be immersed and boiled in an 8-fold volume of distilled water for 2.5 hours. This process will be repeated twice. The extract solution will be pooled and concentrated into granule form. Weight of the resulting granules contained in two 9g-sachet packs (to be taken in one day) is equivalent to 45 g raw herbal materials which are supplied for one day.
Placebo
The placebo granules are prepared to be identical to PGD granules in smell, taste and color.
Beijing Anding Hospital, Beijing
Xijing Hospital, Xian
Department of Psychiatry, Queen Mary Hospital, Hong Kong
Department of Psychiatry, Kowloon Hospital, Kowloon
Kowloon Hospital, Hong Kong
OTHER
Queen Mary Hospital, Hong Kong
OTHER
Capital Medical University
OTHER
Xijing Hospital
OTHER
The University of Hong Kong
OTHER