Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia

PHASE4CompletedINTERVENTIONAL
Enrollment

262

Participants

Timeline

Start Date

May 31, 2013

Primary Completion Date

June 30, 2014

Study Completion Date

June 30, 2014

Conditions
DyspepsiaComplianceDepression
Interventions
DRUG

Omeprazole

Prescribe Omeprazole(20mg, po, qd, 30min before breakfast).

DRUG

Flupentixol-Melitracen(psychological and GI) + Omeprazole

Prescribe Flupentixol and Melitracen Tablets(one tablet, po, qd, 1 hour after breakfast) and Omeprazole (20mg, po, qd, 30min before breakfast).The patients were told that: GI symptoms in FD are attributable to both psychological and GI mechanisms. Flupentixol-Melitracen relieves FD symptoms through both psychological and GI mechanisms.

DRUG

Flupentixol-Melitracen(psychological) + Omeprazole

Prescribe Flupentixol and Melitracen Tablets(one tablet, po, qd, 1 hour after breakfast) and Omeprazole (20mg, po, qd, 30min before breakfast). The patients were told that: GI symptoms were attributable to somatization of their psychological problems; and Flupentixol-Melitracen is an antipsychotic drug and primarily acts centrally to alleviate FD symptoms by regulating the psychological condition.

DRUG

Flupentixol-Melitracen(without explanation) + Omeprazole

Prescribe Flupentixol and Melitracen Tablets(one tablet, po, qd, 1 hour after breakfast) and Omeprazole (20mg, po, qd, 30min before breakfast). The patients were told only that Flupentixol-Melitrace has been proven to be effective in FD treatment and were not provided additional explanations of the relationships between their GI symptoms and their psychological condition and the reasons for the prescription of Flupentixol-Melitrace.

Trial Locations (1)

Unknown

Renji Hospital, Shanghai

All Listed Sponsors
lead

RenJi Hospital

OTHER

NCT01851863 - Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia | Biotech Hunter | Biotech Hunter