MRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma Multiforme

PHASE1CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

August 13, 2013

Primary Completion Date

April 12, 2018

Study Completion Date

May 30, 2018

Conditions
Glioblastoma
Interventions
DEVICE

MRI-guided Laser Heat Ablation (MLA)

DRUG

Doxorubicin

OTHER

Blood draw - dendritic cells

"The second 10 patients enrolled to Arm B:~* before MLA (up to 3 days before)~* 2 weeks after MLA~* 4 weeks after MLA~* every 2 weeks thereafter for up to 3 months after biopsy (provided there is no significant chemotherapy induced cytopenia)"

DEVICE

Dynamic Susceptibility Contrast Magnetic Resonance Imaging

Trial Locations (1)

63110

Washington University School of Medicine, St Louis

All Listed Sponsors
collaborator

The Foundation for Barnes-Jewish Hospital

OTHER

lead

Washington University School of Medicine

OTHER

NCT01851733 - MRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma Multiforme | Biotech Hunter | Biotech Hunter