Local or Regional or General Anesthesia for Hernia Repair: a Randomized Controlled Trial

NACompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

April 30, 2014

Primary Completion Date

November 30, 2015

Study Completion Date

November 30, 2015

Conditions
HerniaAnesthetics Adverse ReactionInflammation
Interventions
PROCEDURE

local anesthesia group

Patients will receive local anesthesia similar to that described by Amid et al. except that 1% lidocaine with adrenaline (1:200,000) will be used instead of a mixture of lidocaine and bupivacaine.

PROCEDURE

spinal anesthesia group

Patients will be positioned in the lateral position and a Whitacre 25 G needle will be inserted at L3-4 intervertebral space and then heavy bupivacaine 0.5% 15 mg will be injected.

PROCEDURE

general anesthesia group

Patients will be induced with propofol 2 mg/kg and fentanyl 1.5 µg /kg. They are then allowed to breathe spontaneously with sevoflurane 2% to 2.5% in a mixture of 60% oxygen through a laryngeal mask. End-tidal concentration of sevoflurane will be adjusted to keep end-tidal sevoflurane 1MAC. Supplemental doses of 25 µg of fentanyl will be administered if intraoperative heart rate and blood pressure are greater than 20% of baseline.

Trial Locations (1)

10700

Siriraj hospital, Bangkoknoi

All Listed Sponsors
lead

Mingkwan Wongyingsinn, MD

OTHER

NCT01845376 - Local or Regional or General Anesthesia for Hernia Repair: a Randomized Controlled Trial | Biotech Hunter | Biotech Hunter