The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy

PHASE4CompletedINTERVENTIONAL
Enrollment

222

Participants

Timeline

Start Date

January 8, 2013

Primary Completion Date

December 17, 2014

Study Completion Date

December 17, 2014

Conditions
Hepatic EncephalopathyCirrhosis
Interventions
DRUG

Rifaximin

Rifaximin will be administered per the dose and schedule specified in the arms.

DRUG

Lactulose

Laculose will be administered per the schedule specified in the respective arm.

Trial Locations (43)

10016

Concorde Medical Group PLLC, New York

New York University Medical Center, New York

Salix Site, New York

10032

Columbia University Medical Ctr. Center for Liver Disease & Transplantation, New York

14642

University of Rochester Strong Memorial Hospital, Rochester

19141

Albert Einstien Medical Center, Philadelphia

23298

VCU/MCV Health Systems, Richmond

28204

Carolina Medical Center, Charlotte

28801

Asheville Gastroenterology Associates, PA, Asheville

31201

Gastroenterology Associates, Macon

33605

Tampa General Medical Group, Tampa

46202

Indiana University, Indianapolis

53792

University of Wisconsin Hospital & Clinics, Madison

55905

Mayo Clinic, Rochester

60611

Salix Site, Chicago

63104

St. Louis University, St Louis

64131

Kansas City Research Institute, Kansas City

70124

Salix Site, Jefferson

71201

Delta Research Partners, LLC, Monroe

73112

Integris Nazh Zuhdi Transplant Institute, Oklahoma City

77030

Research Specialists of Texas, Houston

77090

Amcare Research Inc, Houston

78215

Alamo Medical Research, San Antonio

78229

Methodist Hospital, San Antonio

79761

Salix Site, Odessa

80045

University of Colorado Denver, Aurora

80113

South Denver GI, Englewood

84132

University of Utah Hospital, Salt Lake City

85016

Banner Research, Phoenix

90822

Salix Site, Long Beach

92037

UCSD Clinical & Translational Research Institute, La Jolla

92103

Salix Site, San Diego

92118

Southern California Liver Centers, Coronado

92377

Inland Empire Liver Foundation, Rialto

92501

Salix Site, Riverside

93721

UCSF/Fresno - CRMC, Fresno

94115

Salix Site, San Francisco

32610-0277

University of Florida Hepatology, Gainesville

50309-1453

Central Iowa Hospital Corp, Des Moines

21202-2165

The Center for Liver and Biliary Disease, Baltimore

02115

Brigham and Women's Hospital Division of Gastroenterology & Hepatology, Boston

68198-3285

Univ. of Nebraska Medical Center, Omaha

27599-7584

UNC School of Medicine/Division of Gastroenterology and Hepatology, Chapel Hill

All Listed Sponsors
lead

Bausch Health Americas, Inc.

INDUSTRY

NCT01842581 - The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy | Biotech Hunter | Biotech Hunter