Rituximab for Anti-cytokine Autoantibody-Associated Diseases

PHASE1CompletedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

April 29, 2014

Primary Completion Date

May 6, 2021

Study Completion Date

May 6, 2021

Conditions
Pulmonary Alveolar Proteinosis (PAP)Severe Mucocutaneous Candidiasis
Interventions
DRUG

Rituximab

Subjects will receive intravenous (IV) infusions of rituximab 1 gram on days 1 and 15, and subsequently if indicated up to once a month for 5 months (+/-5 days for each visit) starting approximately on day 42. Subjects whose infections respond positively to the treatment but then relapse may be offered additional treatment.

Trial Locations (1)

20892

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT01842386 - Rituximab for Anti-cytokine Autoantibody-Associated Diseases | Biotech Hunter | Biotech Hunter