Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level

PHASE2CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

July 31, 2013

Primary Completion Date

December 31, 2015

Study Completion Date

December 31, 2015

Conditions
Vitamin D DeficiencyThoracic SurgeryPediatric DisordersHeart Defects, Congenital
Interventions
DIETARY_SUPPLEMENT

Cholecalciferol

The High Dose group is based on the age-specific UL. These doses were chosen to elevate 25OHD well above 50 nmol/L, while minimizing the risk of vitamin D toxicity (e.g. hypercalcemia, hypercalciuria)

Trial Locations (1)

K1H 8L1

Children's Hospital of Eastern Ontario, Ottawa

Sponsors
All Listed Sponsors
collaborator

The Ottawa Hospital

OTHER

collaborator

McGill University

OTHER

collaborator

Children's University Hospital, Ireland

OTHER

collaborator

Ottawa Hospital Research Institute

OTHER

lead

Children's Hospital of Eastern Ontario

OTHER