Proof of Concept Study to Determine the Safety and Antiviral Effect of BZF961 With or Without Ritonavir Boosting in Hepatitis C Virus Infected Patients

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

March 31, 2013

Primary Completion Date

December 31, 2014

Study Completion Date

December 31, 2014

Conditions
Hepatitis C
Interventions
DRUG

BZF961

There will be 2 parts to the study: Part 1: BZF monotherapy. Part 2: Cohort IIa: BZF961 monotherapy at 3 TBD doses; Cohort IIb: BZF961 in combination with ritonavir at TBD doses.

DRUG

Ritonavir

Ritonavir will be given as a boosting agent in Part 2, Cohort IIb in combination with BZF961

DRUG

Placebo

Placebo

Trial Locations (3)

32809

Novartis Investigative Site, Orlando

78215

Novartis Investigative Site, San Antonio

92120

Novartis Investigative Site, San Diego

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY