18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

March 31, 2013

Primary Completion Date

January 31, 2014

Study Completion Date

November 23, 2015

Conditions
Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)Ewing Sarcoma of BoneExtraosseous Ewing SarcomaLocalized Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorMetastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorUntreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions
DRUG

fluorine F 18 fluorothymidine

Undergo 18F-FLT PET

RADIATION

fludeoxyglucose F 18

Undergo 18F-FDG PET

PROCEDURE

positron emission tomography

Undergo 18F-FLT PET and 18F-FDG PET

PROCEDURE

diffusion-weighted magnetic resonance imaging

Undergo DW-MRI

OTHER

laboratory biomarker analysis

Correlative studies

Trial Locations (1)

55905

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER

NCT01825902 - 18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma | Biotech Hunter | Biotech Hunter