Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis

PHASE4CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 28, 2013

Primary Completion Date

June 30, 2014

Study Completion Date

June 30, 2014

Conditions
Sinusitis
Interventions
DRUG

Doxycycline

Subjects with CRSwNP who are not allergic to doxycycline will receive Doxycycline 100mg BID for either 3 or 6 weeks duration.

DRUG

Azithromycin

Subjects with CRS without Nasal Polyposis (CRSwNP)who are not allergic to azithromycin will be given Azithromycin 250mg daily for either 3 or 6 weeks duration.

DRUG

Augmentin

If a subject in any of the study arms is allergic to the medication he/she is supposed to receive, he/she will be given Augmentin 875mg BID for either 3 or 6 weeks duration

Trial Locations (1)

27514

Department of Otolaryngology-Head and Neck Surgery clinics at UNC Hospitals, Chapel Hill

All Listed Sponsors
lead

University of North Carolina, Chapel Hill

OTHER

NCT01825408 - Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis | Biotech Hunter | Biotech Hunter