Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and Aggression

Buspirone/placebo will be given in increasing increments of 15 mg as needed. Subjects will start with 15 mg on day one and end with 60 mg on day 91 or placebo equivalent. Dose is titrated based on treatment response.

The placebo tablets taste and look identical to buspirone.