Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

PHASE3CompletedINTERVENTIONAL
Enrollment

177

Participants

Timeline

Start Date

November 4, 2013

Primary Completion Date

March 31, 2019

Study Completion Date

March 31, 2020

Conditions
Bacterial InfectionBenign NeoplasmMalignant NeoplasmMethicillin-Resistant Staphylococcus Aureus InfectionMyeloid NeoplasmRecurrent Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood Acute Myeloid Leukemia
Interventions
PROCEDURE

Chlorhexidine Gluconate Skin Cleanser

Given CHG cleansing

OTHER

Laboratory Biomarker Analysis

Correlative studies

PROCEDURE

Mild Soap Skin Cleanser

Given control cleansing

OTHER

Questionnaire Administration

Ancillary studies

Trial Locations (59)

10032

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York

10467

Montefiore Medical Center - Moses Campus, The Bronx

10595

New York Medical College, Valhalla

11040

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park

19803

Alfred I duPont Hospital for Children, Wilmington

20010

Children's National Medical Center, Washington D.C.

21215

Sinai Hospital of Baltimore, Baltimore

21287

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore

23298

Virginia Commonwealth University/Massey Cancer Center, Richmond

27157

Wake Forest University Health Sciences, Winston-Salem

30322

Children's Healthcare of Atlanta - Egleston, Atlanta

32207

Nemours Children's Clinic-Jacksonville, Jacksonville

32504

Nemours Children's Clinic - Pensacola, Pensacola

32827

Nemours Children's Hospital, Orlando

33606

Tampa General Hospital, Tampa

33701

Johns Hopkins All Children's Hospital, St. Petersburg

37232

Vanderbilt University/Ingram Cancer Center, Nashville

37403

T C Thompson Children's Hospital, Chattanooga

38105

St. Jude Children's Research Hospital, Memphis

43606

The Toledo Hospital/Toledo Children's Hospital, Toledo

48201

Wayne State University/Karmanos Cancer Institute, Detroit

54301

Saint Vincent Hospital Cancer Center Green Bay, Green Bay

60612

University of Illinois, Chicago

63110

Washington University School of Medicine, St Louis

64108

Children's Mercy Hospitals and Clinics, Kansas City

70118

Children's Hospital New Orleans, New Orleans

70121

Ochsner Medical Center Jefferson, New Orleans

76104

Cook Children's Medical Center, Fort Worth

78207

Children's Hospital of San Antonio, San Antonio

78229

Methodist Children's Hospital of South Texas, San Antonio

University of Texas Health Science Center at San Antonio, San Antonio

78411

Driscoll Children's Hospital, Corpus Christi

78723

Dell Children's Medical Center of Central Texas, Austin

90027

Children's Hospital Los Angeles, Los Angeles

90502

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance

90806

Miller Children's and Women's Hospital Long Beach, Long Beach

91010

City of Hope Comprehensive Cancer Center, Duarte

92868

Children's Hospital of Orange County, Orange

93636

Valley Children's Hospital, Madera

94143

UCSF Medical Center-Parnassus, San Francisco

94158

UCSF Medical Center-Mission Bay, San Francisco

97227

Legacy Emanuel Children's Hospital, Portland

97239

Oregon Health and Science University, Portland

98105

Seattle Children's Hospital, Seattle

98431

Madigan Army Medical Center, Tacoma

99204

Providence Sacred Heart Medical Center and Children's Hospital, Spokane

94609-1809

Children's Hospital and Research Center at Oakland, Oakland

06106

Connecticut Children's Medical Center, Hartford

06520

Yale University, New Haven

04401

Eastern Maine Medical Center, Bangor

02215

Dana-Farber Cancer Institute, Boston

07601

Hackensack University Medical Center, Hackensack

57117-5134

Sanford USD Medical Center - Sioux Falls, Sioux Falls

N6A 5W9

Children's Hospital, London

K1H 8L1

Children's Hospital of Eastern Ontario, Ottawa

M5G 1X8

Hospital for Sick Children, Toronto

H3H 1P3

The Montreal Children's Hospital of the MUHC, Montreal

00912

San Jorge Children's Hospital, San Juan

00926

University Pediatric Hospital, San Juan

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT01817075 - Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant | Biotech Hunter | Biotech Hunter