Assessment of Bone Marrow-derived Cellular Therapy in Progressive Multiple Sclerosis (ACTiMuS)

PHASE2UnknownINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

October 31, 2019

Study Completion Date

October 31, 2019

Conditions
Progressive Multiple Sclerosis
Interventions
OTHER

Early infusion of autologous marrow

Intravenous infusion of autologous bone marrow without prior myeloablation on the day of bone marrow harvest and infusion of autologous blood at one year post-bone marrow harvest

OTHER

Late infusion of autologous marrow

Infusion of blood on day of bone marrow harvest with intravenous infusion of autologous bone marrow without prior myeloablation one year post-bone marrow harvest.

Trial Locations (1)

BS10 5NB

RECRUITING

Southmead Hospital, Bristol

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol Royal Hospital for Children

OTHER

collaborator

University of Bristol

OTHER

collaborator

University of Nottingham

OTHER

collaborator

NHS Blood and Transplant

OTHER_GOV

collaborator

Kenneth and Claudia Silverman Family Foundation

OTHER

collaborator

Multiple Sclerosis Trust

UNKNOWN

collaborator

Medical Research Council

OTHER_GOV

collaborator

Rosetrees Trust

OTHER

collaborator

Catholic Bishops of England and Wales

UNKNOWN

collaborator

Friends of Frenchay

UNKNOWN

lead

North Bristol NHS Trust

OTHER