Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function

NACompletedINTERVENTIONAL
Enrollment

172

Participants

Timeline

Start Date

June 30, 2013

Primary Completion Date

November 30, 2017

Study Completion Date

August 31, 2022

Conditions
Emphysema
Interventions
DEVICE

Spiration Valve System

Subjects assigned to the treatment group will undergo a bronchoscopic procedure to have valves placed in the most diseased lobe of the lung to occlude all segments of the lobe.

OTHER

Medical Management

Stable management is based on the ACP/ACCP/ATS/ERS Guidelines for Management of Stable COPD. Medical management will include management of COPD medications, oxygen use, and pulmonary rehabilitation.

Trial Locations (34)

10065

Cornell NYPH, New York

15213

University of Pittsburgh Medical Center, Pittsburgh

17033

Penn State Milton S. Hershey Medical Center, Hershey

19140

Temple University Hospital, Philadelphia

21201

University of Maryland, Baltimore

23298

Virginia Commonwealth University, Richmond

28203

Carolinas Medical Center, Charlotte

30309

Piedmont Hospital, Atlanta

32216

Mayo Clinic Jacksonville, Jacksonville

33125

Miami VA Healthcare System, Miami

33606

Tampa General Hospital, Tampa

34239

Sarasota Memorial Hospital, Sarasota

37212

Vanderbilt University Medical Center, Nashville

37920

University of Tennessee Medical Center, Knoxville

45219

University of Cincinnati, Cincinnati

48336

Beaumont Botsford Hospital (DCRC), Farmington Hills

53226

Medical College of Wisconsin, Milwaukee

60561

University of Chicago, Chicago

60611

Northwestern Memorial Hospital, Chicago

71130

Louisiana State University Hospital, Shreveport

72901

Sparks Regional Medical Center, Fort Smith

75235

UT Southwestern Medical Center at Dallas, Dallas

77030

Michael DeBakey VA Medical Center, Houston

84132

University of Utah, Salt Lake City

92103

University of California San Diego, San Diego

92505

Kaiser Permanente Riverside Medical Center, Riverside

94115

California Pacific Medical Center, San Francisco

97015

Kaiser Permanente Northwest Medical Center, Clackamas

02215

Beth Israel Deaconess Medical Center, Boston

01805

Lahey Clinic, Burlington

08103

Cooper University Hospital, Camden

05401

Fletcher Allen Medical Center, Burlington

T2N 4Z6

University of Calgary, Calgary

G1V 0A6

Laval University, Québec

All Listed Sponsors
lead

Olympus Corporation of the Americas

INDUSTRY

NCT01812447 - Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function | Biotech Hunter | Biotech Hunter