Alisertib With and Without Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

PHASE2TerminatedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

May 21, 2013

Primary Completion Date

October 14, 2015

Study Completion Date

April 20, 2017

Conditions
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Adult Burkitt LymphomaRecurrent Adult Diffuse Large Cell LymphomaRecurrent Grade 1 Follicular LymphomaRecurrent Grade 2 Follicular LymphomaRecurrent Grade 3 Follicular LymphomaRecurrent Mantle Cell LymphomaRecurrent Marginal Zone LymphomaSplenic Marginal Zone LymphomaWaldenström Macroglobulinemia
Interventions
DRUG

alisertib

Given PO

BIOLOGICAL

rituximab

Given IV

OTHER

laboratory biomarker analysis

Laboratory correlative studies will be performed

Trial Locations (2)

30322

Emory University, Atlanta

43210

Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center, Columbus

Sponsors
All Listed Sponsors
collaborator

Millennium Pharmaceuticals, Inc.

INDUSTRY

lead

Ohio State University Comprehensive Cancer Center

OTHER