Angiotensin II Receptor Blockers, Steroids and Radiotherapy in Glioblastoma

PHASE3CompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

March 29, 2013

Primary Completion Date

January 15, 2015

Study Completion Date

May 15, 2017

Conditions
Newly-diagnosed Glioblastoma
Interventions
DRUG

Losartan

Standard of care (Radiotherapy with concomitant temozolomide followed by monthly cures of temozolomide ) + Losartan or placebo (Arm A or B) 50mg\*2/day until the halting for any reason

DRUG

Placebo

Standard of care (Radiotherapy with concomitant temozolomide followed by monthly cures of temozolomide + Placebo 2/day until the halting for any reason

Trial Locations (1)

93000

Neurology Department - Avicenne Hospital, Bobigny

All Listed Sponsors
collaborator

ANOCEF (french association of neuro-oncologists)

UNKNOWN

lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT01805453 - Angiotensin II Receptor Blockers, Steroids and Radiotherapy in Glioblastoma | Biotech Hunter | Biotech Hunter