Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

November 30, 2005

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2027

Conditions
Post-bariatric Surgery
Interventions
DRUG

exendin-(9-39)

hyperglycemic clamp-meal tolerance test is designed to assess insulin secretion before and after meal ingestion

DRUG

exendin -(9-39)

2-day meal tolerance tests with labeled oral and IV glucose using exendin-(9-39) infusion are designed to evaluate the role of GLP-1 signaling on glucose tolerance and glucose kinetics.

Trial Locations (2)

78207

RECRUITING

Texas Diabetes Institute - University Health System, San Antonio

78229

RECRUITING

South Texas Veterans Health Care System, San Antonio

All Listed Sponsors
lead

The University of Texas Health Science Center at San Antonio

OTHER