Prevention of Renal Failure by Nitric Oxide in Prolonged Cardiopulmonary Bypass.

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

217

Participants

Timeline

Start Date

August 31, 2013

Primary Completion Date

June 30, 2015

Study Completion Date

June 30, 2016

Conditions
Heart Valve DiseasesHeart; Complications, Valve, ProsthesisCardiac Valve Replacement Complication
Interventions
OTHER

inhaled nitric oxide

Nitric oxide administration will commence at the onset of CPB and last for 24 hours. At the end of 24 hours, inhaled NO will be weaned and discontinued while carefully monitoring hemodynamics for a period of 2-4 hours.

OTHER

inhaled Nitrogen

Standard gas including nitrogen (the vehicle of the Nitric oxide) administration will commence at the onset of CPB and last for 24 hours. At the end of 24 hours, inhaled gases will be weaned and discontinued while carefully monitoring hemodynamics for a period of 2-4 hours.

Trial Locations (1)

710032

Xijing Hospital, Xi'an

All Listed Sponsors
lead

Xijing Hospital

OTHER

NCT01802619 - Prevention of Renal Failure by Nitric Oxide in Prolonged Cardiopulmonary Bypass. | Biotech Hunter | Biotech Hunter