62
Participants
Start Date
October 7, 2013
Primary Completion Date
October 31, 2025
Study Completion Date
October 31, 2025
Metformin
500 mg by mouth daily for 4 days on Days 1 - 4 of Cycle 0 and then 2 times a day (about 12 hours apart) every day after that. Metformin taken for 7 - 10 days in Cycle 0 before Cycle 1 begins.
Letrozole
2.5 mg tablet by mouth once daily in a 28 day cycle.
Everolimus
10 mg by mouth once daily in a 28 day cycle.
Sacred Heart Health Systems, Pensacola
Memorial City Medical Center, Houston
Lyndon B Johnson General Hospital, Houston
University of Texas MD Anderson Cancer Center, Houston
The Woman's Hospital of Texas, Houston
MD Anderson Cooper Cancer Center, Voorhees Township
Collaborators (1)
Novartis
INDUSTRY
National Cancer Institute (NCI)
NIH
M.D. Anderson Cancer Center
OTHER