A Study of the Safety and Effectiveness of Irosustat When Added to an AI in ER+ve Locally Advanced or Metastatic Breast Cancer.

PHASE2CompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

October 31, 2012

Primary Completion Date

December 31, 2014

Study Completion Date

December 31, 2014

Conditions
Locally Advanced Breast CancerMetastatic Breast Cancer
Interventions
DRUG

Irosustat

Patients will receive 40mg of Irosustat once daily in addition to the aromatase inhibitor on which they progressed until disease progression or development of unacceptable toxicities.

Trial Locations (9)

CM1 7ET

Mid Essex Hospital Services NHS Trust, Chelmsford

EH1 3EG

NHS Lothian, Edinburgh

G12 0YN

NHS Greater Glasgow and Clyde, Glasgow

L7 8XP

Royal Liverpool and Broadgreen University Hospital, Liverpool

NW3 2QG

Royal Free London, London

TW7 6AF

West Middlesex University Hospital NHS Trust, London

W6 8RF

Imperial College Healthcare NHS Trust, London

WC1E 6BT

University College London Hospitals NHS Foundation Trust, London

M204BX

The Christie NHS Foundations Trust, Manchester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cancer Research UK

OTHER

lead

Imperial College London

OTHER