A Study of the Safety, Pharmacokinetic Drug Interaction and Efficacy of ETC-1002 and Atorvastatin in Subjects With Hypercholesterolemia

PHASE2CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

December 31, 2012

Primary Completion Date

August 31, 2013

Study Completion Date

August 31, 2013

Conditions

Hypercholesterolemia

Interventions

DRUG

ETC-1002

Week 1-2, 60 mg/day; Week 3-4, 120 mg/day; Week 5-6, 180 mg/day; Week 7-8, 240 mg/day

DRUG

Placebo

Placebo once daily for 8 weeks

DRUG

Atorvastatin

Atorvastatin 10mg once daily for 8 weeks

Trial Locations (3)

Richmond

Louisville

Indianapolis