Cytochrome P450-2D6 Screening Among Elderly Using Antidepressants (CYSCE)

PHASE4CompletedINTERVENTIONAL
Enrollment

202

Participants

Timeline

Start Date

February 28, 2013

Primary Completion Date

May 31, 2017

Study Completion Date

June 30, 2017

Conditions
DepressionDepressive DisorderPoor Metabolizer Due to Cytochrome P450 CYP2D6 VariantIntermediate Metabolizer Due to Cytochrome P450 CYP2D6 VariantUltrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Interventions
OTHER

Genotype information accompanied by a drug dosing advice

Dosing advices for deviating genotypes (Poor Metabolizer, Intermediate Metabolizer, Ultrarapid Metabolizer)based on the guidelines of the Royal Dutch Pharmacists Association (KNMP).

Trial Locations (11)

Unknown

GGZ WNB, Halsteren

GGZ Centraal, Ermelo

Lentis, Groningen

University Medical Centre Groningen, Groningen

GGZ Friesland, Leeuwarden

Isala Klinieken, Zwolle

5200ME

Jeroen Bosch Ziekenhuis, 's-Hertogenbosch

5201DZ

Reinier van Arkel groep, 's-Hertogenbosch

1070BB

GGz inGeest, Amsterdam

1851NG

GGZ-NHN, Heiloo

2552KS

Parnassia, The Hague

All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

lead

University of Groningen

OTHER

NCT01778907 - Cytochrome P450-2D6 Screening Among Elderly Using Antidepressants (CYSCE) | Biotech Hunter | Biotech Hunter