Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia

PHASE2CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

October 31, 2012

Primary Completion Date

June 30, 2016

Conditions
DysphagiaAspirationStroke
Interventions
BEHAVIORAL

Dietary and oral hygiene recommendations

DIETARY_SUPPLEMENT

oral TRPV1 agonist

Patients will receive the administration of a TRPV1 agonist (natural capsaicin) supplement before each meal, 3 meals/day, 5 days/week for 2 consecutive weeks. The TRPV1 agonist will be provided by the pharmacy of the center.

DEVICE

pharyngeal electrical stimulation

Includes neuron stimulation treatment of 1 session / day of pharyngeal electrical stimulation of 10 min duration, 3 days/week during 1 week, done at the same center.

DEVICE

transcutaneous electrical stimulation

Trans-cutaneous electrical stimuli will be applied 5 seconds every minute during 1 hour daily session, 5 days/week during 2 consecutive weeks at the same centre.

Trial Locations (1)

08304

Hospital de Mataró, Mataró

All Listed Sponsors
lead

Hospital de Mataró

OTHER

NCT01777672 - Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia | Biotech Hunter | Biotech Hunter