A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk Cardiac Surgery

PHASE2CompletedINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

February 28, 2013

Primary Completion Date

March 31, 2014

Study Completion Date

March 31, 2014

Conditions
Acute Kidney Injury
Interventions
DRUG

ABT-719

1 arm of ABT-719 higher dose, 1 arm of ABT-719 intermediate dose, and 1 arm ABT-719 lower dose

DRUG

Placebo

Placebo infusion

Trial Locations (41)

2100

Site Reference ID/Investigator# 109295, Copenhagen O

5000

Site Reference ID/Investigator# 94955, Odense C

10032

Site Reference ID/Investigator# 83722, New York

15232

Site Reference ID/Investigator# 83734, Pittsburgh

20814

Site Reference ID/Investigator# 83732, Bethesda

22908

Site Reference ID/Investigator# 90614, Charlottesville

23225

Site Reference ID/Investigator# 83725, Richmond

27103

Site Reference ID/Investigator# 87733, Winston-Salem

27710

Site Reference ID/Investigator# 83723, Durham

28054

Site Reference ID/Investigator# 92413, Gastonia

28803

Site Reference ID/Investigator# 89176, Asheville

30322

Site Reference ID/Investigator# 87693, Atlanta

30912

Site Reference ID/Investigator# 87717, Augusta

32207

Site Reference ID/Investigator# 83746, Jacksonville

32216

Site Reference ID/Investigator# 83733, Jacksonville

32610

Site Reference ID/Investigator# 87720, Gainesville

33613

Site Reference ID/Investigator# 89178, Tampa

37923

Site Reference ID/Investigator# 83730, Knoxville

38120

Site Reference ID/Investigator# 101876, Memphis

40536

Site Reference ID/Investigator# 85917, Lexington

43210

Site Reference ID/Investigator# 91813, Columbus

43606

Site Reference ID/Investigator# 83738, Toledo

45219

Site Reference ID/Investigator# 83735, Cincinnati

46237

Site Reference ID/Investigator# 101942, Indianapolis

46804

Site Reference ID/Investigator# 89180, Fort Wayne

48073

Site Reference ID/Investigator# 83744, Royal Oak

48439

Site Reference ID/Investigator# 83750, Grand Blanc

49770

Site Reference ID/Investigator# 83747, Petoskey

53215

Site Reference ID/Investigator# 87739, Milwaukee

53792

Site Reference ID/Investigator# 91814, Madison

55102

Site Reference ID/Investigator# 85913, Saint Paul

63131

Site Reference ID/Investigator# 96455, St Louis

97225

Site Reference ID/Investigator# 91693, Portland

97447

Site Reference ID/Investigator# 89182, Springfield

98405

Site Reference ID/Investigator# 87714, Tacoma

06810

Site Reference ID/Investigator# 83739, Danbury

02115

Site Reference ID/Investigator# 83724, Boston

02135

Site Reference ID/Investigator# 83745, Boston

68198-2315

Site Reference ID/Investigator# 91253, Omaha

07102

Site Reference ID/Investigator# 93673, Newark

DK-8200

Site Reference ID/Investigator# 94956, Aarhus N

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AbbVie

INDUSTRY