Immunotherapy Study in Progressive or Relapsed Non-Small Cell Lung Cancer

PHASE2/PHASE3TerminatedINTERVENTIONAL
Enrollment

135

Participants

Timeline

Start Date

February 28, 2013

Primary Completion Date

May 18, 2016

Study Completion Date

June 18, 2016

Conditions
Non-small Cell Lung CancerProgression of Non-small Cell Lung CancerNon-small Cell Lung Cancer Recurrent
Interventions
DRUG

Docetaxel

Docetaxel given in Arm 1 prior to first progression on study. Given as an option of salvage therapy after first progression on study for Arms 2a and 2b.

BIOLOGICAL

HyperAcute®-Lung Immunotherapy

"HAL-1, HAL-2 and HAL-3 immunotherapy components.~Up to 16 immunizations of 300 million immunotherapy cells."

DRUG

Gemcitabine

Given as an option of salvage therapy after first progression on study for Arms 1, 2a and 2b.

DRUG

Pemetrexed

Given as an option of salvage therapy after first progression on study for Arms 1, 2a and 2b.

Trial Locations (24)

10310

Richmond University Medical Center, Staten Island

24501

Lynchburg Hematology Oncology Clinic, Lynchburg

27103

Wake Forest Baptist Health, Winston-Salem

32610

University of Florida, Gainesville

37920

University of Tennessee Medical Center, Knoxville

38801

North Mississippi Hematology and Oncology Associates at BridgePoint, Tupelo

43210

Ohio State University Comprehensive Cancer Center, Columbus

44195

Cleveland Clinic, Cleveland

44718

Gabrail Cancer Center, Canton

45219

University of Cincinnati, Cincinnati

46202

Indiana University, Indianapolis

46526

Indiana University Health Goshen Center for Cancer Care, Goshen

47713

Deaconess Clinic, Evansville

53792

University of Wisconsin, Madison

54311

Vince Lombardi Cancer Clinic, Green Bay

60005

Illinois Cancer Specialists, Arlington Heights

60611

Northwestern University, Chicago

60637

University of Chicago, Chicago

63110

Washington University School of Medicine, St Louis

64128

Kansas City VA Medical Center, Kansas City

66205

University of Kansas Cancer Center, Fairway

68198

University of Nebraska Medical Center, Omaha

95403

St. Joseph Heritage Healthcare, Santa Rosa

06902

Stamford Hospital, Stamford

Sponsors
All Listed Sponsors
lead

NewLink Genetics Corporation

INDUSTRY

NCT01774578 - Immunotherapy Study in Progressive or Relapsed Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter