Diagnosis of Covert/Minimal Hepatic Encephalopathy by Means of Continuous Reaction Time Measurement

NACompletedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

January 31, 2013

Primary Completion Date

October 31, 2015

Study Completion Date

November 30, 2015

Conditions
Liver CirrhosisHepatic Encephalopathy
Interventions
DRUG

Lactulose and rifaximin

3 months treatment. lactulose 25 Ml x3 per day. Rifaximin (550 mg) x 2 per day.

DIETARY_SUPPLEMENT

Branched Chain amino acids

30 grams of branched chain amino acids (Bramino) per day is given to the patients in the antiHE treatment arm along with lactulose and rifaximin.

OTHER

Placebo

Patients in the placebo-arm receives both placebo-Bramino, placebo-lactulose and placebo-rifaximin.

Trial Locations (2)

5000

Odense University Hospital, Odense

6700

Hospital of South West Jutland, Esbjerg

All Listed Sponsors
collaborator

Region of Southern Denmark

OTHER

collaborator

Odense University Hospital

OTHER

collaborator

Esbjerg Hospital - University Hospital of Southern Denmark

OTHER

lead

Mette Munk Lauridsen

OTHER

NCT01773538 - Diagnosis of Covert/Minimal Hepatic Encephalopathy by Means of Continuous Reaction Time Measurement | Biotech Hunter | Biotech Hunter