Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin Lymphoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

41

Participants

Timeline

Start Date

March 8, 2013

Primary Completion Date

October 15, 2021

Study Completion Date

March 21, 2024

Conditions
AIDS-Related Hodgkin LymphomaAnn Arbor Stage II Hodgkin LymphomaAnn Arbor Stage IIA Hodgkin LymphomaAnn Arbor Stage IIB Hodgkin LymphomaAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage IIIA Hodgkin LymphomaAnn Arbor Stage IIIB Hodgkin LymphomaAnn Arbor Stage IV Hodgkin LymphomaAnn Arbor Stage IVA Hodgkin LymphomaAnn Arbor Stage IVB Hodgkin LymphomaClassic Hodgkin LymphomaHIV Infection
Interventions
DRUG

Brentuximab Vedotin

Given IV

DRUG

Dacarbazine

Given IV

DRUG

Doxorubicin Hydrochloride

Given IV

OTHER

Pharmacological Study

Correlative studies

DRUG

Vinblastine

Given IV

Trial Locations (28)

10065

Memorial Sloan Kettering Cancer Center, New York

10461

Montefiore Medical Center-Einstein Campus, The Bronx

19107

Pennsylvania Hospital, Philadelphia

19111

Fox Chase Cancer Center, Philadelphia

21287

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore

31059

Centre Hospitalier Universitaire (CHU) de Toulouse, Cedex

Chu Purpan, Toulouse

33136

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami

60612

John H Stroger Jr Hospital of Cook County, Chicago

63110

Siteman Cancer Center at Washington University, St Louis

Washington University - Jewish, St Louis

Washington University School of Medicine, St Louis

69310

Centre Hospitalier Lyon-Sud, Pierre-Bénite

70112

Louisiana State University Health Science Center, New Orleans

75010

Hopital Saint Louis, Paris

75012

Hospital Saint-Antoine, Paris

90035

UCLA Center for Clinical AIDS Research and Education, Los Angeles

90095

UCLA / Jonsson Comprehensive Cancer Center, Los Angeles

92093

UC San Diego Moores Cancer Center, La Jolla

92140

Hopital Antoine Beclere, Clamart

94000

Henri Mondor University-Hospital Center, Créteil

95817

University of California Davis Comprehensive Cancer Center, Sacramento

98101

Virginia Mason Medical Center, Seattle

98104

Harborview Medical Center, Seattle

98109

Fred Hutchinson Cancer Center, Seattle

02118

Boston Medical Center, Boston

02215

Beth Israel Deaconess Medical Center, Boston

06202

Hopital l'Archet-CHU de Nice, Nice

All Listed Sponsors
collaborator

The Lymphoma Academic Research Organisation

OTHER

lead

National Cancer Institute (NCI)

NIH

NCT01771107 - Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin Lymphoma | Biotech Hunter | Biotech Hunter