NCT01768663View on ClinicalTrials.gov

A Phase 1 Study to Examine the Drug-Drug Interaction of Ciprofloxacin, Itraconazole, and Rifampin on the Combination of Lumacaftor With Ivacaftor in Healthy Adult Subjects

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

January 31, 2013

Primary Completion Date

September 30, 2013

Conditions

Cystic Fibrosis

Interventions

DRUG

Lumacaftor

tablet, 200mg taken every 12 hours

DRUG

Ivacaftor

tablet, 250mg taken every 12 hours

DRUG

Ciprofloxacin

750 mg taken every 12 hours

DRUG

Itraconazole

200mg taken once daily

DRUG

Rifampin

600mg taken once daily

Trial Locations (1)

Unknown

Evansville

All Listed Sponsors

lead

Vertex Pharmaceuticals Incorporated

INDUSTRY

NCT01768663 - A Phase 1 Study to Examine the Drug-Drug Interaction of Ciprofloxacin, Itraconazole, and Rifampin on the Combination of Lumacaftor With Ivacaftor in Healthy Adult Subjects | Biotech Hunter | Biotech Hunter